The idea of tiny changes cumulated over many steps is an immensely powerful idea, capable of explaining an enormous range of things that would be otherwise inexplicable. How did snake venom get its start? Many animals bite, and any animal's spit contains proteins which, if they get into a wound, may cause an allergic reaction. Even so-called non-venomous snakes can give bites that cause a painful reaction in some people. There is a continuous, graded series from ordinary spit to deadly venom.